ESMO 2021 Lung Cancer – Natasha B. Leighl

Natasha B. Leighl outlines recent insights gained in terms of circulating tumor DNA in patients with advanced NSCLC, the impact of liquid biopsy on the time to treatment, advantages of complementary testing, the clinical utility of plasma ctDNA testing in the context of treatment monitoring and future first-line treatment options for patients with advanced NSCLC.

Here is the full ESMO 2021 Lung Cancer report.

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Expansion of treatments and insights in the early-stage disease setting

The management of patients with stage I-III non–small-cell lung cancer (NSCLC) is still characterized by a high unmet medical need as up to 60 % experience disease relapse despite treatment with curative intent [1]. IMpower010 was the first phase III study of cancer immunotherapy to demonstrate a disease-free survival (DFS) benefit in the adjuvant situation after complete resection and platinum-based chemotherapy.

Preface

With the World Conference on Lung Cancer that took place on 8th–14th September 2021 and the ESMO Congress on 16th–21st September, two prestigious cancer congresses have offered a wealth of new preclinical and clinical information in the field of lung cancer. Results from pivotal studies were updated, and fascinating novel treatment approaches were presented to large audiences around the world.