ESMO IO 2021 – David McDermott
David McDermott deals with the question if combination therapy is superior to single agent PD-1/PD-L1 blockade in the adjuvant setting, highlights tools/biomarkers for appropriate patient selection for immune checkpoint inhibitor therapies, future strategies to potentially overcome resistance to ICIs, potential new outcome parameters for clinical trials investigating ICIs and highlights the most relevant findings presented at ESMO IO 2021 in terms of immuno-oncology.
Here is the full ESMO IO 2021 report.
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Immune checkpoint blockade combined with chemotherapy in solid tumors
Non-small cell lung cancer (NSCLC) is a severe disease with poor outcomes since the majority of patients present with stage IV disease at diagnosis. Approved treatment options in the first-line setting of advanced NSCLC (aNSCLC) with wildtype EGFR/ALK include bevacizumab - a VEGF targeting monoclonal antibody - and PD-1/PD-L1 inhibitors in combination with chemotherapy.
Preface
The ESMO Immuno-Oncology Congress 2021 took place as a hybrid event either in Geneva or online from 8th to 11th December 2021. Compared with the annual ESMO scientific congress, this meeting focused exclusively on the most exciting new data in the promising field of immuno-oncology. In total, 1,124 participants from 67 countries attended one of the 31 on-demand sessions featuring over 193 abstracts, 178 e-posters, 146 presentations and 20 educational sessions.