ESMO 2021 Solid Tumor – Javier Cortés
Javier Cortés highlights the superiority of trastuzumab deruxtecan compared to trastuzumab emtansine in patients with HER2-positive metastatic breast cancer and the resulting future therapy algorithm, potential combinations in the management of patients with HER2-negative breast cancer and the clinical relevance of immunotherapy-based approaches in the treatment of triple-negative breast cancer.
Here is the full ESMO 2021 Solid Tumors report.
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Highlights in cervical cancer
In 2020, more than 600,000 new cases of cervical cancer were diagnosed. Its mortality rate reached 57 % with more than 340,000 deaths; cervical cancer was the ninth leading cause of cancer-related death worldwide and therefore a concerning global health issue. In young women (aged 15 to 44 years), it is the second most common cancer and cause of cancer death.
Novel approaches in gastric/gastroesophageal cancer
Gastric cancer (GC) is the fifth most common cancer and the third leading cause of cancer death worldwide. Although gastroesophageal junction (GEJ) cancer, a form of gastric cancer arising in the area of the digestive tract where esophagus and stomach connect, has a lower prevalence than GC, it is continuously rising.
Colorectal cancer – personalized medicine for a heterogeneous disease
Metastatic colorectal cancer (mCRC), a major cause of death in the Western world, continuous to have a 5-year survival rate below 15 %, with microsatellite stable (MSS) mCRC representing the greatest clinical challenge due to its poorly characterized immune microenvironment and immune response.
New horizons in colorectal cancer
Colorectal cancer (CRC) is the second leading cause of cancer death worldwide. About 20 % of CRC patients are diagnosed at the metastatic stage (mCRC), with a 5-year survival rate of 14 %.
Preface
For the second time, the ESMO scientific meeting took place virtually from 16th - 21st September 2021. Despite the challenges of the pandemic, the ESMO committee received an increased number of submitted abstracts compared to last year.