ESMO 2021 Lung Cancer – Oliver Gautschi

Oliver Gautschi highlights the most relevant findings presented at ESMO 2021 in terms of lung cancer, innovative treatment approaches currently tested for use in patients with unresectable malignant pleural mesothelioma, immunotherapeutic approaches in the setting of thymoma and thymic carcinoma and summarizes potential strategies for the management of RET-positive NSCLC.

Here is the full ESMO 2021 Lung Cancer report.

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Expansion of treatments and insights in the early-stage disease setting

The management of patients with stage I-III non–small-cell lung cancer (NSCLC) is still characterized by a high unmet medical need as up to 60 % experience disease relapse despite treatment with curative intent [1]. IMpower010 was the first phase III study of cancer immunotherapy to demonstrate a disease-free survival (DFS) benefit in the adjuvant situation after complete resection and platinum-based chemotherapy.

Preface

With the World Conference on Lung Cancer that took place on 8th–14th September 2021 and the ESMO Congress on 16th–21st September, two prestigious cancer congresses have offered a wealth of new preclinical and clinical information in the field of lung cancer. Results from pivotal studies were updated, and fascinating novel treatment approaches were presented to large audiences around the world.