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WCLC congress 20222025-01-28T16:41:57+01:00

WCLC 2022 – hybrid, vienna

Lecture Board: Maximilian Hochmair, MD; Michael Thomas, MD
Medical Writer: Dr. Judith Moser

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All downloads from WCLC 2022

Full report (english)

EXPERT VIDEOS

All video interviews from virtual WCLC 2022

Filiz Oezkan depicts the most important factors influencing the choice of treatment in patients with PD-L1-positive NSCLC, explains how the 50 % PD-L1 threshold affects the treatment selection and explains which treatment options appear favorable in the setting of PD-L1 levels below 1 % while also taking into account possible challenges associated with biomarker testing for PD-L1 in NSCLC.

Alexander Louie explains which modes of imaging can be particularly helpful when clinicians face unique diagnostic challenges in lung cancer patients with pneumonitis after chemoradiotherapy and immunotherapy. Moreover, he summarizes what needs to be considered regarding pneumonitis treatment and highlights current and future pneumonitis research areas.

Maximilian Hochmair highlights relevant study data in the field of EGFR-mutated advanced lung cancer, novel therapies in the management of KRAS p.G12C mutation as well as MET exon 14 skipping mutations in NSCLC. He draws attention to antibody drug conjugates in the management of NSCLC patients as well as the optimal treatment sequence in the ALK-positive setting.

Federico Cappuzzo discusses the effectiveness and limitations of minimal residual disease (MRD) assessment in the detection of patients with early-stage lung cancer at low risk of relapse and highlights which clinical investigations regarding the clinical impact of MRD assessments in solid tumors are ongoing and what we can expect from them in the future.

Helmut Popper talks about the characteristics of the recently defined molecular subtypes of small-cell lung cancer (SCLC), outlines if this subtyping is suitable for therapeutic decision-making and gives an overview about potential new therapeutic targets in the field of SCLC.

Julia Rotow summarizes the achievements of EGFR tyrosine kinase inhibitors in the neoadjuvant therapy of lung cancer regarding multiple clinical outcomes, discusses if modification of the disease biology will be a feasible treatment goal in the setting of EGFR-directed neoadjuvant treatment sometime and talks about the individualization of neoadjuvant treatment of oncogene-driven lung cancer.

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