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ESMO congress Solid Tumors 20212025-01-27T13:33:16+01:00

ESMO 2021 Solid Tumors – virtual

 

Lecture Board: Daniel Catenacci, MD; Chiara Cremolini, MD, PhD; Sara A. Hurvitz, MD; Krishnansu S. Tewari, MD; Romain Varnier, MD;
Medical Writer: Florence Boulmé, PhD; Eva Eckelhart, PhD
Publishing Editor: Anna Fenzl, PhD

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All downloads from ESMO 2021 Solid Tumors – virtual

ESMO 2020 Solid Tumors English Slide Kit

Slide Kit Lung and gastrointestinal cancers

ESMO 2020 Solid Tumors English

Full report (english)

EXPERT VIDEOS

All video interviews from ESMO Solid Tumors 2021

Yelena Y. Janjigian talks about the practice-changing results obtained in the CheckMate 649 trial and how the proportion of patients with advanced gastric cancer and esophageal adenocarcinoma who receive multiple treatment lines rather than just one or two can be increased. Biomarker-targeted therapies, precision medicine approaches for advanced G/GEJ cancers, the significance of chemotherapy as well as the duration of maintenance therapy are discussed, too.

Chiara Cremolini gives an overview of strategies that might become available in the future to enhance the efficacy of immunotherapies in the setting of microsatellite-stable metastatic colorectal cancer, how to increase the proportion of patients with metastatic colorectal cancer who receive multiple treatment lines, the optimal continuum of care in 2021 in metastatic colorectal cancer and how to predict progressive disease.

Javier Cortés highlights the superiority of trastuzumab deruxtecan compared to trastuzumab emtansine in patients with HER2-positive metastatic breast cancer and the resulting future therapy algorithm, potential combinations in the management of patients with HER2-negative breast cancer and the clinical relevance of immunotherapy-based approaches in the treatment of triple-negative breast cancer.

Ian Chau depicts the most interesting trial results in the field of esophageal cancer at the ESMO 2021 congress, gives an outlook on personalized approaches in the setting of esophageal squamous-cell carcinoma with regard to biomarkers for checkpoint inhibitors as well as potential further improvements of the prognosis of patients with esophageal cancer.

Ken Kato summarizes combination regimens currently investigated in the neoadjuvant treatment of patients with esophageal cancer and outlines how immunotherapy has changed the first-line treatment standards in patients with esophageal squamous-cell carcinoma and which further developments are expected for the first-and second-line setting in the future.

The ESMO congress has provided amazing new data on gastroesophageal cancer, and great contributions by different authors all over the world have been presented. Patients with advanced gastric cancer used to have a median overall survival of less than 1 year when treated with conventional chemo­therapy. For the first time, this was prolonged to more than 1 year due to the ­addition of checkpoint inhibition.

Andrés Cervantes • MD • PhD, Department of Medical Oncology, Hospital Clinic Universitario, Biomedical Research institute INCLIVA, University of Valencia, Spain
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