ESMO 2023 Lung Cancer – James R. M. Black
James R. M. Black provides an overview of the potential of ctDNA in pre-operative disease stratification for early lung cancer by highlighting data from an ultra-sensitive and specific ctDNA approach. Considering the challenges of comprehensive tissue sampling and that subclones may evade tumor biopsy detection due to undersampling of metastatic sites at relapse, he finally discusses what insights ctDNA-based methods could provide into the process of metastasis spread.